Comparison of Conventional and Neutrosophic Methods for Statistical Power Analysis and Effect Size in Clinical Research

Authors

  • Vennila J Associate Professor, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal-576 104. Karnataka. India.
  • Basker P Associate Professor, Department of Mathematics, Chandigarh University, Punjab – 140 413. India.
  • Kripa Josten Research Scholar, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal-576 104. Karnataka. India.
  • Prakash P Associate Professor, Department of Computer Science, Kristu Jayanti College, Bengaluru. Karnataka. India.
  • Keerthi Vijayan Assistant Professor, Department of Statistics, Kristu Jayanti College, Bengaluru. Karnataka. India.
  • Menaka B Assistant Professor, Department of Mathematics, Kristu Jayanti College, Bengaluru. Karnataka. India.
  • Prabu Raja G Associate Professor, Department of Exercise and Sports Sciences, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal-576 104. Karnataka. India.

Keywords:

Effect size, power analysis, clinical study, conventional statistical analysis, neutrosophic approach

Abstract

The study investigates the integration of conventional statistical methods with 
neutrosophic techniques for effect size and statistical power analysis in clinical research. It addresses 
a significant gap in applying neutrosophic methodologies to complex datasets characterized by 
uncertainty and variability. Conventional methods, such as Cohen’s d, assume well-defined data, 
which limits their effectiveness in real-world clinical scenarios. Neutrosophic methods incorporate 
degrees of truth, falsity, and indeterminacy and are more suitable for analyzing uncertain and 
inconsistent clinical data. For instance, when comparing blood pressure reduction between a 
Treatment Group and a Control Group, conventional methods yield an effect size of 3.00 and a 
power of 99%. In contrast, neutrosophic methods result in an effect size of 13.46 and a power of 
100%, highlighting their ability to manage data complexities better. The findings emphasize the 
need to integrate neutrosophic techniques into clinical analysis to improve effect size and power 
estimation accuracy and reliability, especially in studies with variable data. However, the study is 
limited to a specific dataset, and further research is needed across different clinical domains. 
Neutrosophic methods might also require advanced resources and expertise, which could be 
challenging in some settings. This study presents a novel approach that improves our 
understanding of clinical outcomes. 

 

DOI: 10.5281/zenodo.15151223

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Published

2025-06-01

How to Cite

Vennila J, Basker P, Kripa Josten, Prakash P, Keerthi Vijayan, Menaka B, & Prabu Raja G. (2025). Comparison of Conventional and Neutrosophic Methods for Statistical Power Analysis and Effect Size in Clinical Research. Neutrosophic Sets and Systems, 83, 381-396. https://fs.unm.edu/nss8/index.php/111/article/view/6121